Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains.
نویسندگان
چکیده
A novel theranostic divalent vancomycin analog using a planar 1,8-diazapyrene moiety as a rigid scaffold exhibits potent and selective antibacterial activity against Gram (+) bacteria including vancomycin-resistant strains, while having minimal influence on Gram (-) bacteria and mammalian cells. Moreover, this theranostic analog can be also applied for selective two-photon fluorescence imaging of Gram (+) bacteria.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 52 25 شماره
صفحات -
تاریخ انتشار 2016